The presented article is devoted to the review of modern data on pyoderma in dogs caused by Staphylococcus pseudintermedius. The article systematically examines the features of modern views on the spread, causes, pathogenesis, clinical signs and treatment of the pathology. It is worth noting that modern views on pyoderma in dogs are closely interrelated with the concept of the microbiota of the skin and should be considered together. Since the skin is a vital barrier that protects the internal environment of the body from external environmental influences, the adoption of close interaction between the immune system and the skin microbiota is extremely important for the further development and application of the most effective data for pathology therapy. The purpose of the article is to review modern sources and the latest world research on the problems of skin infection caused by Staphylococcus pseudintermedius, as well as its significance for humans and animals. The author uses her own research on the effectiveness of antimicrobial shampoo with 4% chlorhexidine in relation to secondary bacterial dermatitis in dogs in order to demonstrate the therapy of pyoderma using local antiseptics without systemic antibacterial drugs and to prove the effectiveness of this treatment option. Thus, this review article is devoted to the analysis of information about the causative agent of canine pyoderma - Staphylococcus pseudintermedius, the features of pathogenesis, the problem of antibiotic resistance.
pyoderma, staphylococcus pseudintermedius, dogs, veterinary dermatology, infectious diseases
1. Kobayashi T. Epithelial-immune crosstalk with the skin microbiota in homeostasis and atopic dermatitis-a mini review. Veterinary Dermatology. 2021;6:147.
2. Deng Z. Grainyheadlike transcription factors: guardians of the skin barrier. Veterinary dermatology. 2021;6:152.
3. Ferrer L. Whole genome sequencing and de novo assembly of Staphylococcus pseudintermedius: a pangenome approach to unravelling pathogenesis of canine pyoderma. Veterinary Dermatology. 2021;6:654-663. EDN: https://elibrary.ru/OYGING
4. Suvorova O.A., Vorob'eva E.Ya., Suvorova M.V. Piodermiya sobak i koshek // Innovacii molodyh - razvitiyu sel'skogo hozyaystva. 2018. № 36. S. 158-168. EDN: https://elibrary.ru/VALAMU
5. Tomashov D.B. Struktura i vidovoy sostav vozbuditeley kokkovyh infekciy sobak // Agrarnaya nauka - sel'skomu hozyaystvu. 2019. № 12. S. 362-364. EDN: https://elibrary.ru/KCHKLA
6. Akulova I.A., Petuhova E.I. Mikrobiocenoz sobak i koshek // NIRS - pervaya stupen' v nauku. 2017. № 26. S. 185-188. EDN: https://elibrary.ru/YWIRMT
7. Lynch S.A. The complex diseases of Staphylococcus pseudintermedius in canines: where to next? Veterinary sciences. 2021;1:11. EDN: https://elibrary.ru/VTYCEQ
8. Smith J.T. Population genomics of Staphylococcus pseudintermedius in companion animals in the United States.Communications Biology. 2020;1:282. EDN: https://elibrary.ru/QRIIHC
9. Bhooshan S. Staphylococcus pseudintermedius: An undocumented, emerging pathogen in humans. GMS Hygiene and Infection Control. 2020;32:138-146.
10. Carroll K.C. From canines to humans: Clinical importance of Staphylococcus pseudintermedius. PLoS pathogens. 2021;12:e1009961.
11. Balbuckaya A.A., Skvorcov V.N., Dmitrenko O.A. Chuvstvitel'nost' k antimikrobnym preparatam i geny faktorov patogennosti u izolyatov Staphylococcus pseudintermedius, vydelennyh ot zdorovyh sobak // Veterinariya. 2015. № 8. S. 28-27. EDN: https://elibrary.ru/UDKLYB
12. Marsella R. Advances in our understanding of canine atopic dermatitis. Veterinary Dermatology. 2021;6:151.
13. Sykes J.E. Antimicrobial drug use in dogs and cats. Antimicrobial Therapy in Veterinary Medicine. 2013;22:473-494.
14. Samtsov A.V. Topical therapy for pyoderma. Vestnik dermatologii i venerologii. 2020;5:59-64. EDN: https://elibrary.ru/MAQAJT
15. Al'tova V.K. Vidovoy sostav i chuvstvitel'nost' k antibakterial'nym preparatam vozbuditeley piodermii sobak // Nauka i Obrazovanie. 2021. № 2. 221 s. EDN: https://elibrary.ru/MMEQBM
16. Zayakina D.I. Differencial'naya diagnostika i lechenie poverhnostno bakterial'nogo follikulita sobak // Nauchnye issledovaniya studentov v reshenii aktual'nyh problem APK. 2022. № 8. S. 36-40. EDN: https://elibrary.ru/WNVPFA
17. Squires R.A. Bacteriophage therapy for challenging bacterial infections: achievements, limitations and prospects for future clinical use by veterinary dermatologists. Veterinary Dermatology. 2021;6:158.
18. Kupriyanova L.I., Bagrinceva E.G., Petrova O.V. Ocenka effektivnosti shampunya s hlorgeksidinom 4% pri vtorichnyh mikrobnyh porazheniyah u sobak s hronicheskimi allergicheskimi dermatozami // Rossiyskiy veterinarnyy zhurnal. 2019. № 9. S. 51-56.
