Candidiasis of the digestive tract (CDT) of geese, against the background of activation throughout the digestive system of Candida albicans, leads to the development of dysbiosis, immunodeficiencies, followed by inclusion in the pathology of all body systems. Existing methods of antimycotic therapy have only a further suppressive effect on the stressed body of birds. The paper presents the results of studying the functional depletion of the pancreas, one of the main digestive organs, against the background of the development of deep CDT in geese. It has been established that timely enzyme therapy with a microbial preparation Lithicase in combination with the probiotic Subtilis C (Research Institute “Probioticsˮ, Moscow) and propolis contributes to the dynamic recovery, in the direction of physiological values, of the production of digestive enzymes of the pancreas. The level of pancreatic lipase in the blood, in comparison with the data from sick and untreated geese, increased dynamically over the experimental periods in 14, 30, 60, 90 and 120 days. at 2.57; 4,63; 71,8; 111.3 and 119.7 times; amylase - in 2.1; 3,4; 7,5; 10.5 and 19.5 times; proteases - in 1.66; 2,08; 2,66; 3.15 and 3.9 times, indicating the restoration of the metabolism of fats, carbohydrates and proteins in the body of geese.
geese, candidiasis, pancreas, lipase, amylase, protease, lithicase, probiotic propolis
1. Ayurzanaeva M.V., Naletova L.A., Maksarova D.D. Ekologo-fiziologicheskie osobennosti pischevaritel'noy funkcii podzheludochnoy zhelezy ptic s razlichnymi tipami pitaniya // Estestvennye nauki. Fiziologiya. 2017. № 4(61). S. 112-115.
2. Vertiprahov V.G., Grozina A.A., Karamushkina S.V. Morfo-biohimicheskie issledovaniya krovi u sel'skohozyaystvennoy pticy. Blagoveschensk. 2021. 134 s.
3. Dilekova O.V. Vidovye osobennosti anatomicheskogo stroeniya i topografii podzheludochnoy zhelezy sel'skohozyaystvennyh zhivotnyh // Uchenye zapiski Kazanskoy gosudarstvennoy akademii veterinarnoy mediciny im. N.E. Baumana. 2010. T. 203. S. 1-3. EDN: https://elibrary.ru/SBDLPB
4. Efimochkina N.R., Sedova I.B., Sheveleva S.A., Tutel'yan V.A. Toksigennye svoystva mikroskopicheskih gribov // Vestnik Tomskogo gosudarstvennogo universiteta. Biologiya. 2019. № 45(6). S.6-33. EDN: https://elibrary.ru/HZPKXC
5. Mannapova R.T., Shayhulov R.R., Mannapova A.G. Vosstanovlenie funkcional'nyh mehanizmov immunnogo otveta pri kandidamikozah gusey i na fone enzimoterapii s adaptogenami // Estestvennye i tehnicheskie nauki. 2022. № 1. S. 110-118. EDN: https://elibrary.ru/HPWCXD
6. Sachivkina N.P., Lenchenko E.M., Haytovich A.B. Ocenka intensivnosti obrazovaniya bioplenok mikroskopicheskimi gribami roda Candida // Krymskiy zhurnal eksperimental'noy i klinicheskoy mediciny. 2018. T. 8, № 3. S. 58-65. EDN: https://elibrary.ru/YUQTQL
7. Shayhulov R.R., Mannapova R.T. Narushenie balansa vitaminov pri kandidamikozah gusey // Izvestiya Samarskoy gosudarstvennoy sel'skohozyaystvennoy akademii. 2023. № 1. S. 71-78. EDN: https://elibrary.ru/ACBYQS
8. Gruber-Dorninger C., Novak V., Nagl V., Berthiller F. Emerging Mycotoxins: Beyond Traditionally Determined Food Contaminants. Journal of Agricultural and Food Chemistry. 2017;65(33):7052-7070. EDN: https://elibrary.ru/IWWGWC
9. Lofgren L., Riddle J., Dong Y., Kuhnem P.R. et al. A high proportion of NX-2 genotype strains are found among Fusarium graminearum isolates from northeastern. Eur. J. Plant Pathology. 2018.
10. Zinedine A., Fernandez-Franzon M., Manes J., Manyes L. Multi-mycotoxin contamination of couscous semolina commercialized in Morocco. Food Chemistry. 2017;214:440-446.
