Conjunctivitis and keratoconjunctivitis can occur in animals for many reasons: infectious, invasive, mechanical, chemical and physical factors. Keratoconjunctivitis may be a primary disease, or it may be a consequence of another disease not related to the visual analyzer. Eye diseases in young animals (up to 90 days of life) are rare, however, in specialized complexes they are registered at a level of 0.8%. Treatment of keratoconjunctivitis on the farm is carried out using various schemes. In particular, this study uses two schemes: with the systemic use of broad-spectrum antibiotics, with simultaneous retrobulbar novocaine blockade according to Avrorov. The basis for the choice of treatment regimens was the forms of drugs and their routes of administration, as well as the sensitivity of the pathogen to certain antibacterial substances. To form the experimental and control groups, 10 calves of 3 months of age with similar body weight, identical housing and feeding conditions, and having the following symptoms of the onset of the disease were selected: general depression, loss of appetite, hyperemia and swelling of the conjunctiva and eyelids, corneal opacity, blepharospasm and profuse lacrimation. Based on the results obtained, it was established that the use of a treatment regimen for the experimental group with subcutaneous injection into the upper eyelid of “Draxin” and the application of eye ointment “Mizofen-F” showed greater therapeutic effectiveness - in the animals of the experimental group, the dynamics of recovery were more intense, the recovery of the last animal occurred already on Day 6, in animals of the control group on day 8, clinical recovery was observed in four animals. The authors of the article propose to use a relatively new scheme with the introduction of the antibiotic “Draxin” into the upper eyelid and the placement of “Mizofen-F” ophthalmic ointment into the conjunctival space. In the experiment, the authors proved the economic feasibility of the proposed new treatment regimen. Economic efficiency per ruble of costs is 1.9 times higher when using the treatment regimen for the experimental group than for the treatment regimen for the control group: 3.37 rubles and 1.75 rubles, respectively.
conjunctivitis, keratoconjunctivitis, calves, treatment, effectiveness
1. Baygazanov A.N., Abdullina E.A. Infekcionnyy keratokon'yunktivit (moraksellez) krupnogo rogatogo skota v Vostochnom Kazahstane // Evraziyskiy soyuz uchenyh. 2020. № 9-3(78). S. 49-53. EDN: https://elibrary.ru/SPTYQB
2. Gagarin E.M., Glazunova L.A. Infekcionnyy keratokon'yunktivit krupnogo rogatogo skota i effektivnost' ego lecheniya // Sovremennye napravleniya razvitiya nauki v zhivotnovodstve i veterinarnoy medicine: materialy Mezhdunarodnoy nauchno-prakticheskoy konferencii posvyaschennoy 60-letiyu kafedry tehnologii proizvodstva i pererabotki produktov zhivotnovodstva i 55-letiyu kafedry inostrannyh yazykov, Tyumen', 25 aprelya 2019 goda. Tyumen': FGBOU VO Gosudarstvennyy agrarnyy universitet Severnogo Zaural'ya, 2019. S. 81-84. EDN: https://elibrary.ru/WJKSCM
3. Dupleva L.Sh., Spiridonov G.N., Husainov I.T. Vakcina protiv infekcionnogo keratokon'yunktivita krupnogo rogatogo skota na osnove bakteriy Moraxellabovis i Moraxellabovoculi // Aktual'nye voprosy sovershenstvovaniya tehnologii proizvodstva i pererabotki produkcii sel'skogo hozyaystva. 2019. № 21. S. 387-389. EDN: https://elibrary.ru/SAQRZT
4. Dyul'ger G.P., Tabakov G.P. Osnovy veterinarii: uchebnoe posobie dlya vuzov. 3-e izd., ster. SPb.: Lan', 2020. 476 s. EDN: https://elibrary.ru/PZLVBB
5. Ermolaev V.A., Sapozhnikov A.V. Issledovanie mikrobnogo fona slizistyh obolochek glaz molodnyaka KRS // Izvestiya OGAU. 2019. № 3(77). S. 205-206. EDN: https://elibrary.ru/MAIQAM
6. Kalagova O.V. Lechenie i profilaktika specificheskih kon'yunktivo-keratitov u krupnogo rogatogo skota // Nauchnoe obespechenie sel'skogo hozyaystva gornyh i predgornyh territoriy: materialy Vserossiyskoy studencheskoy nauchno-prakticheskoy konferencii, Vladikavkaz, 25-27 noyabrya 2020 goda. Vladikavkaz: Gorskiy gosudarstvennyy agrarnyy universitet, 2020. S. 189-191. EDN: https://elibrary.ru/TZPVXU
7. Kozikov I.N. Sovremennyy podhod k lecheniyu infekcionnogo keratokon'yunktivita u krupnogo rogatogo skota // Agrarnaya nauka. 2019. № 7. S. 24-25. EDN: https://elibrary.ru/HPJSQY
8. Koshlyak V.V., Zaharov A.S. Techenie i klinicheskaya kartina, vozrastnaya i sezonnaya dinamika infekcionnogo keratokon'yunktivita u krupnogo rogatogo skota // MNIZh. 2021. № 8-2(110). S. 36-41. EDN: https://elibrary.ru/GXYBRW
9. Krapivina E.V., Pesenko E.A. Effektivnost' dvuh shem lecheniya infekcionnogo keratokon'yunktivita u telyat // Aktual'nye problemy innovacionnogo razvitiya zhivotnovodstva: sbornik trudov Mezhdunarodnoy nauchno-prakticheskoy konferencii, Bryansk, 28-29 maya 2020 goda. Bryansk: Bryanskiy gosudarstvennyy agrarnyy universitet, 2020. S. 159-163. EDN: https://elibrary.ru/PQMEZK
10. Nikitin I.N. Organizaciya veterinarnogo dela: uchebnoe posobie. 4-e izd., pererab. i dop. SPb.: Lan', 2022. 288 s. EDN: https://elibrary.ru/IPHVRY
11. Pashkova E.V., Shahova V.N., Schukina M. Patologii glaz u krupnogo rogatogo skota // Novosti nauki v APK. 2019. № 3(12). S. 123-126. EDN: https://elibrary.ru/QDPVBZ
12. Salimov V.A. Atlas. Patologiya i differencial'naya diagnostika faktornyh bolezney molodnyaka sel'skohozyaystvennyh zhivotnyh: uchebnoe posobie. 2-e izd., pererab. SPb.: Lan', 2022. 384 s.
13. Sorokoletova V.M., Denk N.A. Opyt lecheniya infekcionnogo keratokon'yunktivita u telyat v ZAO "Skala" Kolyvanskogo rayona Novosibirskoy oblasti // Aktual'nye problemy agropromyshlennogo kompleksa: sb. trudov nauch.-prakt. konf. prepodavateley, aspirantov, magistrantov i studentov Novosibirskogo gosudarstvennogo agrarnogo universiteta, Novosibirsk, 29-30 oktyabrya 2018 goda. Tom 1. Vyp. 3. Novosibirsk: Zolotoy kolos, 2018. S. 122-125. EDN: https://elibrary.ru/YLOUMP
14. Yurtaykina K.A. Meropriyatiya po likvidacii infekcionnogo keratokon'yunktivita krupnogo rogatogo skota v OOO "BMK" Bryanskoy oblasti // Problemy intensivnogo razvitiya zhivotnovodstva i ih reshenie: Bryansk, 25-26 marta 2021 goda. Bryansk: Bryanskiy gosudarstvennyy agrarnyy universitet, 2021. S. 447-451. EDN: https://elibrary.ru/DBTBNZ
15. Yanchenko M.M. Epizootologiya i mery bor'by s infekcionnym keratokon'yunktivitom krupnogo rogatogo skota v usloviyah APH "Miratorg" // Nauchnye problemy proizvodstva produkcii zhivotnovodstva i uluchsheniya ee kachestva: materialy XXXV nauch.-prakt. konf. studentov i aspirantov, Bryansk, 17-19 aprelya 2019 goda / Bryanskiy gosudarstvennyy agrarnyy universitet. Bryansk: Bryanskiy gosudarstvennyy agrarnyy universitet, 2019. S. 17-20. EDN: https://elibrary.ru/YXCEBH
16. Pedanova E.S., Mashnin D.V. Keratokon'yunktivit KRS: osobennosti techeniya, lecheniya i profilaktiki zabolevaniya v usloviyah skotovodcheskih hozyaystv // Nauchno-innovacionnoe razvitie veterinarnoy nauki i praktiki: materialy Nacional'noy (Vserossiyskoy) nauch.-prakt. konf., Omsk, 10 noyabrya 2022 goda. Omsk: Omskiy gosudarstvennyy agrarnyy universitet im. P.A. Stolypina, 2022. S. 120-123. EDN: https://elibrary.ru/MCVEBR
17. Avdeyuk S.E., Trofimov I.G. Diagnostika i klinicheskie priznaki keratokon'yunktivita u telyat // Sovremennye tendencii razvitiya veterinarnoy nauki i praktiki: sb. materialov Vserossiyskoy (nacional'noy) nauch.-prakt. konf. fakul'teta veterinarnoy mediciny IVMiB FGBOU VO Omskiy GAU, Omsk, 27 aprelya 2023 g. Omsk: Omskiy gosudarstvennyy agrarnyy universitet imeni P.A. Stolypina, 2023. S. 179-182. EDN: https://elibrary.ru/MVRYMG
