THE EXPERIENCE IN USING TOPICAL AGENTS AND METHODS TO STIMULATE REPARATIVE OSTEOGENESIS OF POST-TRAUMATIC BONE DEFECTS IN SMALL DOMESTIC ANIMALS

S V CHERNIGOVA; T V TAGANOVA; S Y. CHERNIGOV; YU V CHERNIGOV

UDC

619

THE EXPERIENCE IN USING TOPICAL AGENTS AND METHODS TO STIMULATE REPARATIVE OSTEOGENESIS OF POST-TRAUMATIC BONE DEFECTS IN SMALL DOMESTIC ANIMALS

Published in Vestnik of Omsk SAU · Pages 177–184 · Rubric: VETERINARY AND ZOOTECHNY

EDN: OZLTRO

Received: 06.12.2025 Accepted: 15.12.2025 Published: 25.12.2025

Authors

S V CHERNIGOVA

T V TAGANOVA

S Y. CHERNIGOV

YU V CHERNIGOV

S V CHERNIGOVA

Omsk State Agrarian University named after P.A. Stolypin

T V TAGANOVA

Omsk State Agrarian University named after P.A. Stolypin

S Y. CHERNIGOV

Omsk State Agrarian University named after P.A. Stolypin

YU V CHERNIGOV

Omsk State Agrarian University named after P.A. Stolypin

ABSTRACT

Research studies the problems of treating animals with traumatic damage to the skeleton bones. Analyzed materials and methods used as bone tissue implants stimulating the formation of bone regenerate and aimed at ossification. Long process of healing tubular bones fractures, is the main prerequisite for the search and development of treatment methods and stimulation of bone tissue formation process. Currently, methods of directed stimulation of reparative regeneration of the bone matrix are used to prevent complications, minimize the recovery period, and create a favorable environment for bone tissue regeneration by using calcium phosphate, calcium silicate, and their combinations. The slow recovery of post-traumatic bone defects requires additional stimulation of reparative ossification, as there are cases where the lost bone tissue does not regenerate. Natural and synthetic autografts and allografts are used for bone tissue reconstruction, which must meet a wide range of requirements, including biocompatibility and the need to stimulate bone tissue induction, conduction, and regeneration. Hydroxyapatite, an osteosynthetic material, is used as a reconstructive bone graft that stimulates reparative processes. An inorganic analogue of the mineral bone matrix, hydroxyapatite vollastant, increases bone mineralization and the rate of osteointegration after integration into the bone tissue structure. Bibliographic resources analysis has revealed a description of isolated cases when using hydroxyapatite vollastant to stimulate the reparative regeneration of animal bone tissue, which leads to the conclusion about the prospects of using composites containing calcium silicates and phosphates and the need to study the mechanism of bone-plastic materials action.

KEYWORDS

animals, surgery, osteogenesis, bone tissue regeneration, hydroxyapatite

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Oksana Shumakova

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Elena Rodomazova

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CHERNIGOVA S. V., TAGANOVA T. V., CHERNIGOV S. Y., CHERNIGOV Y. V. THE EXPERIENCE IN USING TOPICAL AGENTS AND METHODS TO STIMULATE REPARATIVE OSTEOGENESIS OF POST-TRAUMATIC BONE DEFECTS IN SMALL DOMESTIC ANIMALS // . 2025. pp. 177-184. EDN: OZLTRO. (Date of access 19.08.2026).

MLA

S V CHERNIGOVA, TAGANOVA T. V., CHERNIGOV S. Y., CHERNIGOV Y. V.. "THE EXPERIENCE IN USING TOPICAL AGENTS AND METHODS TO STIMULATE REPARATIVE OSTEOGENESIS OF POST-TRAUMATIC BONE DEFECTS IN SMALL DOMESTIC ANIMALS." (2025): 177-184. EDN: OZLTRO.

APA

CHERNIGOVA S. V., TAGANOVA T. V., CHERNIGOV S. Y., CHERNIGOV Y. V. (2025). THE EXPERIENCE IN USING TOPICAL AGENTS AND METHODS TO STIMULATE REPARATIVE OSTEOGENESIS OF POST-TRAUMATIC BONE DEFECTS IN SMALL DOMESTIC ANIMALS. , 177-184. EDN: OZLTRO.

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{{cite journal | author = CHERNIGOVA S. V., TAGANOVA T. V., CHERNIGOV S. Y., CHERNIGOV Y. V. | title = THE EXPERIENCE IN USING TOPICAL AGENTS AND METHODS TO STIMULATE REPARATIVE OSTEOGENESIS OF POST-TRAUMATIC BONE DEFECTS IN SMALL DOMESTIC ANIMALS | journal = | year = 2025 | pages = 177-184 }} EDN: OZLTRO

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THE EXPERIENCE IN USING TOPICAL AGENTS AND METHODS TO STIMULATE REPARATIVE OSTEOGENESIS OF POST-TRAUMATIC BONE DEFECTS IN SMALL DOMESTIC ANIMALS

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